PEPTIDE GLOSSARY
Key terms and definitions used in peptide research.
- Amino Acid
- Organic molecules that serve as the building blocks of peptides and proteins. There are 20 standard amino acids.
- Bacteriostatic Water
- Sterile water containing 0.9% benzyl alcohol used for reconstituting lyophilized peptides. Inhibits bacterial growth.
- Bioavailability
- The proportion of a substance that enters circulation and is able to have an active effect when introduced into the body.
- DAC (Drug Affinity Complex)
- A modification that extends the half-life of a peptide by binding it to albumin in the blood. Used in CJC-1295 DAC.
- GLP-1 (Glucagon-Like Peptide-1)
- An incretin hormone involved in glucose metabolism and appetite regulation. Targeted by peptides like Retatrutide.
- GIP (Glucose-Dependent Insulinotropic Polypeptide)
- An incretin hormone that stimulates insulin secretion. Retatrutide is a triple agonist targeting GIP, GLP-1, and glucagon receptors.
- Half-Life
- The time required for the concentration of a substance to decrease by half. Determines dosing frequency in research protocols.
- In Vitro
- Latin for "in glass." Refers to studies performed in a controlled environment outside a living organism, such as in a test tube or petri dish.
- Lyophilized
- Freeze-dried. Peptides are commonly supplied in lyophilized (powder) form for stability during storage and shipping.
- MOA (Mechanism of Action)
- The specific biochemical interaction through which a peptide produces its pharmacological effect.
- Neuroprotective
- Refers to mechanisms and strategies aimed at protecting nerve cells from damage, degeneration, or impairment of function.
- Peptide
- A short chain of amino acids (typically 2–50) linked by peptide bonds. Smaller than proteins but biologically active.
- Reconstitution
- The process of dissolving a lyophilized peptide powder in a suitable solvent (usually bacteriostatic water) to create a solution.
- Subcutaneous
- Beneath the skin. A common route of administration for peptide research involving injection into the fatty tissue layer.
- Thymosin
- A family of peptides originally isolated from the thymus gland. TB-500 (Thymosin Beta-4) is a key member involved in tissue repair.